Yongzhou Huamao Biotechnology Co., Ltd.

Oleanolic acid

Product Name:Oleanolic acid extract

Source:  olive leaf

Cas No.: 508-02-1

Molecular formula:C30H48O3

Molecular weight:456

Melting point:306-308°C

Appearence：yellow green to pale yellow powder.

specification: 30%,40%,50%,60%,70%.80%

Testing Method:HPLC

Storage: Store in a well-closed container away from moisture and the sunlight

package:25kg/drum(plastic bag and Aluminum vacuum packing plastic bags)

Function:

1  Alleviating liver injury: oleanolic acid as pentacyclic  triterpenoids  has protective effects on rat acute and chronic liver injury caused by carbon tetrachloride . After treatment, swelling of mi.tochondria and rough endoplasmic expansion of the network is restored. Also allows acute and chronic liver damage hepatocyte ballooning degeneration, necrosis and inflammation was reduced. Reduce the accumulation of liver triglycerides, increase the amount of glycogen

2 lower serum alanine aminotransferase activity: oleanolic acid has the effect of decrease enzyme on Acute and chronic hepatitis and cirrhosis of the liver of animals

3 lower serum globulin, and histological findings of the liver was observed to reduce the inflammation-related consistent.

4 to promote the regeneration of liver cells: The number of mitotic activity in rat liver residues will be increased by using oleanolic acid, higher than the degree of regeneration, suggesting that having a role in promoting cell regeneration.

5. Reduce the brain of rats with liver homogenates tyrosine levels: Since brain homogenates tyrosine levels were significantly decreased to suppress the generation of false neurotransmitters, it is conducive to the prevention and treatment of hepatic encephalopathy.

6. Inhibition of hepatic fibrosis: The rats oleanolic acid treatment of liver fibrosis, liver fibrosis and significantly reduce severe, reducing hepatic collagen content, suggesting that have prevented liver.

7. Oleanolic acid on mice mononuclear phagocyte system, macrophage phagocytosis and experimental arthritis was significantly inhibited, but the opposite sex humoral immunity and antigen-binding cells affected. Enhance immune and growth inhibition of S180 tumor strain.

8. Chromosome damage has a protective effect on experimental atherosclerosis have a preventive effect, but also to correct the protein metabolism.

Attention                                                           

1. a small number of patients with dry mouth, diarrhea, abdominal discomfort, symptomatic treatment may disappear.

2. individual patients with mild decrease platelet resume after the withdrawal.